Bovine-type saralasin, -Ang II, exhibited a greater inhibitory effect on body weight loss than human-type saralasin, -Ang II. Saralasin inhibited Ang II-induced body weight loss. To determine if the Ang II receptors were involved in this Ang II-induced effect, the worms were treated with the nonselective Ang II receptor inhibitor, saralasin. Ang II decreased the body weight of the worms in a time- and dose-dependent manner, whereas Ang I had no effect. tubifex worms were exposed to Ang I or Ang II dissolved in artificial pond water.
We investigated the effects of Ang I and Ang II on body fluid volume in the freshwater sludge worm, Tubifex tubifex (Annelida, Oligochaeta, Tubificidae), which does not require blood-feeding. It has been unclear whether the downregulating effect of Ang II in leeches is caused by their blood-feeding behavior. Ang II upregulates body fluid volume in clam worms and slugs (marine and terrestrial organisms), but downregulates it in blood-sucking leeches. Effect of angiotensin II on body fluid volume of the freshwater oligochaete Tubifex tubifex via the angiotensin II receptor.Biojournal of Science and Technology.Volume 3,2016Īngiotensin (Ang) II upregulates body fluid volume in vertebrates however, it produces varying effects in invertebrates. Tsutomu Nakagawa, Ryousuke Satou, Yusuke Oda, Fumiaki Suzuki, Yukio Nakamura † Present Affiliation: Department of Physiology and the Hypertension and Renal Center of Excellence, Tulane University School of Medicine, New Orleans, LA 0112, USAĭate of Acceptance: Tuesday, March 8, 2016ĭate of Published: Sunday, March 20, 2016įaculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanĪngiotensin, Angiotensin II receptor, Annelid, Body fluid homeostasis, Invertebrate, Renin-angiotensin system Tsutomu Nakagawa 1,2,*, Ryousuke Satou 2,†, Yusuke Oda 1, Fumiaki Suzuki 1,2, Yukio Nakamura 1,2ġ Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University, Gifu, JapanĢ United Graduate School of Agricultural Science, Gifu University, Gifu, Japan
Volume 3, P-ISSN:2412-5377, E-ISSN:2410-9754, Article ID:m150005 Research Article Effect of angiotensin II on body fluid volume of the freshwater oligochaete Tubifex tubifex via the angiotensin II receptor
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